The years of the Bush administration saw better economic times in Russia, as Vladimir Putin brought a degree of stability to the country, but in foreign policy, the former KGB man Putin saw his country suffer (what were in his eyes) repeated indignities. The US embarked on wars in Afghanistan and Iraq. NATO and the EU's borders raced eastwards, pushing up against the Russian frontier itself. The fruits of Clinton's air war against Serbia (Russia's long-standing friend and ally) were reaped by Kosovar independence. George W barely missed an opportunity to kick the Russian bear in Poland, the Czech Republic and Georgia. In the dying days of the crippled Bush presidency the bear gnarled, briefly, over the latter.
And while Obama and Secretary of State Clinon famously (embarrassingly now, looking back) tried to "reset" relations with Russia, preoccupied with Libya, Syria and a "pivot to Asia", when the Obama administration did pay attention to Europe, its focus was on the crisis in eurozone.